making a difference
Genetics, Genomics, Nanotechnology, and more
Science has been interesting to me for most of my lifetime, but it wasn’t until my first child was born that I shifted from “interested” to “involved.” My eldest daughter was diagnosed with Systemic Onset Juvenile Idiopathic Arthritis (SoJIA – originally called Juvenile Rheumatoid Arthritis, or JRA) when she was 15 months old, which also happened to be about six months into the start of my old Consulting company and in the middle of a very critical Y2K ERP system upgrade and rehosting project. It was definitely a challenging time in my life.
At that time, there was very little research on JRA because it was estimated there were only 30,000 children affected by the disease, and the implication was that funding research would not have a positive ROI. This was also a few years before the breakthroughs of biological medicines like Enbrel for children.
One of the things that I learned was that this disease could be horribly debilitating. Children often had physical deformities as a result of this disease. Even worse, the systemic type that my daughter has could result in premature death. As a first-time parent, imagining that type of life for your child was extremely difficult.
Luckily, the company I had just started was taking off, so I decided to find ways to make a tangible difference for all children with this disease. We decided to take 50% of our net profits and use them to fund medical research. We aimed to fund $1 million in research and find a cure for Juvenile Arthritis within the next 5-7 years.
As someone new to “major gifts” and philanthropy, I quickly learned that some gifting vehicles were more beneficial than others. While most organizations wanted you to start a fund (which we did), the impact from that tended to be more long-term and less immediate. I met someone passionate, knowledgeable, and successful in her field who showed me a different and better approach (here’s a post that describes that in more detail).
I no longer wanted to blindly give money and hope it was used quickly and properly. Rather, I wanted to treat these donations like investments in a near-term cure. In order to be successful, I needed to understand research from both medical and scientific perspectives in these areas. That began a new research and independent learning journey in completely new areas.
There was a lot going on in Genetics and Genomics at the time (here’s a good explanation of the difference between the two). My interest and efforts in this area led to a position on the Medical and Scientific Advisory Committee with the Arthritis Foundation. With the exception of me, the other members were talented and successful physicians who were also involved with medical research. We met quarterly, and I did ask questions and made suggestions that made a difference. But, unlike everyone else on the committee, I needed to study and prepare for 40+ hours for each call to ensure that I had enough understanding to add value and not be a distraction.
A few years later we did work for a Nanotechnology company (more info here for those interested). The Chief Scientist wasn’t interested in explaining what they did until I described some of our research projects on gene expression. He then went into great detail about what they were doing and how he believed it would change what we do in the future. I saw that and agreed. I also started thinking of the potential for leveraging nanotechnology with medicine.
While driving today, I was listening to the “TED Radio Hour” and heard a segment about entrepreneur Richard Resnick. It was exciting because it got me thinking about this again – a topic I haven’t thought about for the past few years (the last time, I was contemplating how new analytics products could be useful in this space).
There are efforts today with custom, personalized medicines that target only specific genes for a specific outcome. The genetic modifications being performed on plants today will likely be performed on humans in the near future (I would guess within 10-15 years). The body is an incredibly adaptive organism, so it will be very challenging to implement anything that is consistently safe and effective long-term. But that day will come.
It’s not a huge leap from genetically modified “treatment cells” to true nanotechnology (not just extremely small particles). Just think, machines that can be designed to work independently within us to do what they are programmed to do and, more importantly, identify and understand adaptations (i.e., artificial intelligence) as they occur and alter their approach and treatment plan accordingly based on changes and findings. This is extremely exciting. It’s not that I want to live to be 100+ years old – because I don’t. But, being able to do things that positively impact the quality of life for children and their families is a worthy goal from my perspective.
My advice is to always continue learning, keep an open mind, and see what you can personally do to make a difference. You will never know unless you try.
Note: Updated to fix and remove dead links.
Are you Visionary or Insightful?
Having great ideas that are not understood or validated is pointless, just as being great at “filling in the gaps” to do amazing things does not accomplish much if what you are building achieves little toward your needs and goals. This post is about Dreaming Big and turning those dreams into actionable plans.
Let me preface this post by stating that both are important and complementary roles. But, if you don’t recognize the difference between the two, it becomes much more challenging to execute and realize value/gain a competitive advantage.
The Visionary has great ideas but doesn’t always create plans or follow through on developing the idea. There are many reasons why this happens (distractions, new interests, frustration, lack of time), so it is good to be aware of that, as this type of person can benefit by being paired with people willing and able to understand a new idea or approach, and then take the next steps to flesh out a high-level plan to present that idea and potential benefits to key stakeholders. People may view them as aloof or unfocused.
The Insightful sees the potential in an idea, helps others understand the benefits and gain their support, and often creates and executes a plan to prototype and validate the idea – killing it off early if the anticipated goals are unachievable. They document, learn from these experiences, and become more and more proficient with validating the idea or approach and quantifying the potential benefits. They are usually very pragmatic.
Neither of these types of people is affected by loss aversion bias.
I find it amazing how frequently you hear someone referred to as being Visionary, only to see that the person in question could eliminate some of the noise and “see further down the road” than most people. While this skill is valuable, it is more akin to analytics and science than art. Insight usually comes from focus, understanding, intelligence, and being open-minded. Those qualities matter in both business and personal settings.
On the other hand, someone truly visionary looks beyond what is already illuminated and can, therefore, be detected or analyzed. It’s like a game of chess where the visionary person is thinking six or seven moves ahead. They are connecting the dots for the various future possibilities while their competitor is still thinking about their next move.
Interestingly, this can be a very frustrating situation for everyone.
- The Visionary with an excellent idea may become frustrated because they feel an unmet need to be understood.
- The people around that visionary person become frustrated, wondering why that person isn’t able to focus on what is important or why they fail to see/understand the big picture.
- Others view the visionary ideas and suggestions as tangential or irrelevant. It is only over time that the others understand what the visionary person was trying to show them – often after a competitor has started executing a similar idea.
- The Insightful wanting to make a difference can feel constrained in static environments, offering little opportunity for change and improvement.
Both Insightful and Visionary people feel that they are being strategic. Both believe they are doing the right thing. Both have similar goals. What’s truly ironic is they may view each other as the competition rather than seeing the potential of collaborating.
A strong management team can positively impact creativity by fostering a culture of innovation and placing these people together to work towards a common goal. Providing little time and resources to explore an idea can lead to remarkable outcomes. When I had my consulting company, I sometimes joked, “What would Google do?” to describe that amazing things were possible and waiting to be done.
The insightful person may see a payback on their ideas sooner than the visionary person, and that is due to their focus on what is already in front of them. It may be a year or more before what the visionary person has described shifts to the mainstream and into the realm of insight – hopefully before it reaches the realm of common sense (or worse yet, is entirely passed by).
I recommend that people create a system to gather ideas, along with a description of what the purpose, goals, and advantages of those ideas are. Foster creative behavior by rewarding people for participation regardless of what becomes of the idea. Review those ideas regularly and document your commentary. You will find good ideas with luck – some insightful and possibly even visionary.
Look for commonalities and trends to identify the people who can cut through the noise or see beyond the periphery and the areas having the greatest innovation potential. This approach will help drive your business to the next level.
You never know where the next good idea will come from. Efforts like these provide growth opportunities for people, products, and profits.
Where Ideas, Experiences, and Lessons Learned Intersect 